Tenecteplase

Definition: Tenecteplase, sold under the brand name Tnkase among others, is an enzyme used as a thrombolytic drug. Tenecteplase is a tissue plasminogen activator (tPA) produced by recombinant DNA technology using an established mammalian cell line (Chinese hamster ovary cells). Tenecteplase is a 527 amino acid glycoprotein developed by introducing the following modifications to the complementary DNA for natural human tPA: a substitution of threonine 103 with asparagine, and a substitution of asparagine 117 ... source: Wikipedia

ID

387066007

ID date

3 Aug 2005

Previous ID

4390311000001108

Name

Tenecteplase